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Cold Sores

Oral Herpes · Fever Blister

The Facts

Cold sores - also known as fever blisters - are caused by a virus. They usually appear on the lips. They are highly contagious but not dangerous. About 60% of the population have suffered cold sores at some point in their lives. On average, people who get cold sores have two or three episodes a year, but this figure can vary significantly from person to person.

Causes

The virus that causes cold sores is herpes simplex 1, a cousin of herpes simplex 2, which causes the well-known sexual disease. About 80% of the people in North America have dormant (inactive) herpes 1 virus living permanently in their body. The virus typically resides in a dormant state within the nerve cells of your spinal cord. The body's immune system is normally able to keep the virus in its inactive state. When an infected person is exposed to a "trigger", or if the immune system is weakened, then the virus quickly multiplies, and spreads down the nerve cell and out onto the skin, usually on the lips. This produces the characteristic tingling sensation and subsequent clusters of blisters.

Specific triggers include:

  • cold weather
  • fever, such as from stomach flu or other infections
  • menstrual periods
  • mental or physical stress
  • physical irritation of the lips (e.g., following a visit to the dentist)
  • sunlight or sunburn

You can catch the virus if you come into direct contact with the cold sore blisters or the fluid inside them, which contains a high number of the viruses. This can easily happen through touching the hands of someone who has touched their blisters. Once the blisters have stopped oozing or have crusted over, the person is no longer contagious.

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The contents of this site are for informational purposes only and are meant to be discussed with your physician or other qualified health care professional before being acted on. Never disregard any advice given to you by your doctor or other qualified health care professional. Always seek the advice of a physician or other licensed health care professional regarding any questions you have about your medical condition(s) and treatment(s). This site is not a substitute for medical advice.

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